Fine together

Can you use vitamin C and niacinamide together?

Updated 5 October 2026

The "never mix vitamin C and niacinamide" rule is one of the most repeated skincare myths. It traces back to old research that doesn't reflect how these ingredients are used today.

Where the myth came from

Early studies found that niacinamide and ascorbic acid could react to form a complex, and that niacinamide could convert to nicotinic acid — which can cause temporary flushing. Those findings came from heated solutions and older, less stable forms of the ingredients, not a serum sitting on your face at room temperature.

What we know now

Modern formulas are stable enough that many serums contain both, and using them one after the other is a normal, gentle routine. Niacinamide is generally well tolerated and can help support the skin barrier.

If you do flush

Some people get a little redness or warmth from niacinamide itself, usually at higher concentrations. That's about your skin and the percentage, not the combination. A lower-strength niacinamide, or a few minutes between the two, is the easy fix.

Common questions

Can I use niacinamide and vitamin C together?
Yes. The warning against it came from old research with unstable forms and heat, and many current serums contain both.
Which goes first, vitamin C or niacinamide?
Thinnest texture first is the usual rule, and it rarely matters much. Plenty of people apply vitamin C, then a niacinamide serum, then moisturiser.
Why does my face go red with niacinamide?
Some people flush from niacinamide itself, usually at higher strengths. A lower-percentage product often fixes it.

Popular examples

The most-discussed products in each category, with Australian prices.

General information, not medical advice. For a skin condition, or anything prescribed, talk to your GP, pharmacist or a dermatologist.